HORDB

ID: hor000457
Uniprot ID: E9G0B6
Protein name: Allatostatin A4
Gene name: NA
Organism: Daphnia pulex (Water flea)
Family: Allatostatin family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Daphnia (genus), Daphniidae (family), Anomopoda (infraorder), Cladocera (suborder), Diplostraca (order), Phyllopoda (subclass), Branchiopoda (class), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005184 neuropeptide hormone activity
GO BP: GO:0007165 signal transduction
GO CC: NA

Sequence: NPTKYNFGL
Length: 9(130-138)
Propeptide: MLFLSTALFLLVALLQSSQCTDVNNDSSVIEAVGAGGGDSQAKAESLASAEDKLSALTADGMATRARYFKSFGGNPTGDPNLNIYSFGLGKRTSRSYSINPYSFGLGKRGGNAKSYPQQIPYSFGLGKRNPTKYNFGLGKRPDRFGFGLGKRNLKDDDLDQWLNDEEYSQFDDTEEEIEGREDDSQEIMDVNKRSQMAAGQQQQQQQQAFFPSHLQSAFYGGPFMSNLARANTHALGKSRTFNQQAATHDLPNLG
Signal peptide: MLFLSTALFLLVALLQSSQC
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor000457_AF2.pdb

hor000457_ESM.pdb

Mass:	119605	Formula:	C49H72N12O14
Absent amino acids:	ACDEHIMQRSVW	Common amino acids:	N
pI:	9.3	Basic residues:	1
Polar residues:	5	Hydrophobic residues:	2
Hydrophobicity:	-92.22	Boman Index:	-1270
Half-Life:	1.4 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	43.33
Instability Index:	-1101.11	Extinction Coefficient cystines:	1490
Absorbance 280nm:	186.25

PubMed ID: 21830762
Title: Genomics, Transcriptomics, and Peptidomics of Daphnia Pulex Neuropeptides and Protein Hormones